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Mtmr inhibitor
Mtmr inhibitor








Sirolimus use in liver transplant recipients with hepatocellular carcinoma: a randomized, multicenter, open-label phase 3 trial. Geissler EK, Schnitzbauer AA, Zulke C, Lamby PE, Proneth A, Duvoux C, et al. Early experience with sirolimus in lung transplant recipients with chronic allograft rejection. 2004 4(12):2001–6.Ĭahill BC, Somerville KT, Crompton JA, Parker ST, O’Rourke MK, Stringham JC, et al.

mtmr inhibitor

Comparative effects of sirolimus and mycophenolate mofetil on erythropoiesis in kidney transplant patients. 2006 12(19):3114–8.Īugustine JJ, Knauss TC, Schulak JA, Bodziak KA, Siegel C, Hricik DE. Conversion to sirolimus immunosuppression in liver transplantation recipients with hepatocellular carcinoma: report of an initial experience. Zhou J, Fan J, Wang Z, Wu Z-Q, Qiu S-J, Huang X-W, et al. Anaemia, microcytosis and sirolimus-is iron the missing link? Nephrol Dial Transpl. Sofroniadou S, Kassimatis T, Goldsmith D. A worldwide, phase III, randomized, controlled, safety and efficacy study of a sirolimus/cyclosporine regimen for prevention of acute rejection in recipients of primary mismatched renal allografts. Sirolimus is associated with impaired hematopoiesis in heart transplant patients? A retrospective analysis.

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McDonald MA, Gustafsson F, Almasood A, Barth D, Ross HJ. Posttransplant anemia: the role of sirolimus. 1999 67(7):1036–42.įishbane S, Cohen DJ, Coyne DW, Djamali A, Singh AK, Wish JB. Sirolimus European Renal Transplant Study Group. Sirolimus (rapamycin)-based therapy in human renal transplantation: similar efficacy and different toxicity compared with cyclosporine. Groth CG, Backman L, Morales JM, Calne R, Kreis H, Lang P, et al. Everolimus-based, calcineurin-inhibitor-free regimen in recipients of de-novo kidney transplants: an open-label, randomised, controlled trial. Efficacy of sirolimus compared with azathioprine for reduction of acute renal allograft rejection: a randomised multicentre study. Molecular mechanisms of mTOR-mediated translational control. mTOR signaling in growth control and disease.

mtmr inhibitor

Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase. Kuo CJ, Chung J, Fiorentino DF, Flanagan WM, Blenis J, Crabtree GR. Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases. PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase. Taxonomy of the producing streptomycete and isolation of the active principle. Rapamycin (AY-22,989), a new antifungal antibiotic.










Mtmr inhibitor